Bridging Basic and Clinical Pharmacology
PRESENTATIONS

 

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Paper reference Paper Title
FC01.1.1 Andrew Walubo

Clinical pharmacology in developing countries: overview of current status and future trends.
FC01.1.2 Folke Sjöqvist

Promoting clinical pharmacology in developing countries through education and research training
FC01.1.3 Simon Maxwell

Update of the WHO publication on clinical pharmacology 1970: what we learned from the process and main outcomes
FC01.1.4 Andrew L Gray

Is WHO's Essential Medicines List contributing to rational medicines use in developing countries?
FC01.1.6 Meeta Burande

Comparison of efficacy of ORS + Zn verses ORS + Zn + Saccharomyces Boulardii strain in treatment of acute non infective diarrhea in Indian children
FC01.4.3 Lembit Rägo

WHO Programme for International Drug Monitoring as an effective  framework for strengthening national pharmacovigilance systems
FC02.1.3 Hendrik W van Veen

Molecular pharmacology of the breast cancer resistance protein (ABCG2)
FC02.3.4 Stefan Broer

SLC6 amino acid transporters
FC02.4.2 Ingolf Cascorbi

Clinical consequences of transporter variants
FC03.1.3 Peter A McNaughton

Modulation of TRP channels: impact on pain sensation
FC03.1.4 Sulayman D Dib-Hajj

Voltage sensitive sodium channels in chronic pain states
FC03.2.2 Slobodan M Todorovic

Pharmacological regulation of T-type calcium channels in peripheral pain pathways
FC04.1.2 Olaf H Klungel

Natural experiments in pharmacoepidemiology
FC04.1.3 Til Stürmer

Treatment decisions and propensity scores
FC04.1.4 Robert J Glynn

Healthy starters, sick stoppers, and the value of new user designs with active referents in pharmacoepidemiology
FC04.2.3 Stephen JW Evans

An international perspective on screening for adverse effects of drugs and vaccines – how far can and should active surveillance go?
FC04.3.2 Stephen JW Evans

Are the available research methods sufficiently valid to address current benefit-risk issues on medicinal products?
FC04.3.3 Marieke de Bruin

New approaches to fill the methods gap in pharmacovigilance
FC04.4.1 Trent D Stephens

The impact of thalidomide and its revival as a vital medicine Lessons learned from history
FC04.4.2 Per Damkier

Pharmacological considerations of drug teratogenicity – why animal studies are not sufficient
FC04.4.3 Corinne de Vries

Unique methodological features in the pharmacoepidemiology of birth defects
FC04.4.4 Lolkje TW de Jong-van den Berg

Determining drug effects - Clinical considerations when establishing birth outcomes
FC05.2.1 Heinrich Taegtmeyer

Insulin resistance: marker or mediator of increased cardiovascular risk?
FC05.2.3 Steen Dalby Kristensen

Antithrombotic treatment in patients with type 2 DM
FC05.3.2 Fiona M Gribble

GLP-1 secretion as a prerequisite for the antidiabetic activity of DPP-4 inhibitors: can it be modified?
FC06.1.1 Michael Sanguinetti

The cardiac hERG channel and arrhythmogenesis
FC06.1.2 Penelope A Boyden

Would modulating intracellular Ca be antiarrhythmic?
FC06.2.2 Jean-Marc Davy

Dronedarone for control of ventricular rate during atrial fibrillation: the ERATO study
FC06.2.4 Eva Delpón

Kv1.5 blockers for atrial fibrillation
FC06.3.1 Lionel Opie

Metabolic therapy for heart failure
FC06.3.2 Juan Tamargo

New therapeutic targets in heart failure
FC06.4.4 Mark E Anderson

Rescuing a failing heart
FC07.2.1 Amin Rostami-Hodjegan

Can we predict pharmacokinetics (PK) in disease populations?
FC07.2.2 Mats O Karlsson

Integrated models for the glucose – insulin system
FC07.2.3 Blanca Rodriguez

Heart modelling in drug development
FC07.3.2 Marc Pfister

Modeling and simulation in clinical drug development at Bristol-Myers Squibb
FC07.4.3 Yuki Ando

Role of modelling and simulation for drug approval in Asia
FC07.4.4 Siv Jönsson

Exposure-response and disease modelling from a regulatory view
FC08.1.1 Delphine Behr-Roussel

Animal models for sexual dysfunction and cardiovascular disease
FC08.1.3 Javier Angulo

Treatment of sexual dysfunction associated with cardiovascular disease
FC08.1.4 Graham Jackson

Effects of cardiovascular drugs on sexual function
FC08.1.5 Jackie D Corbin

Phosphodiesterase type 5 and inhibitors – an update
FC08.3.2 Christopher H Fry

Modulation of electromechanical coupling in the bladder
FC09.1.2 Christian Taube

The mast cell as a target for anti-asthma drugs
FC09.2.1 Marc Feldmann

TNF-α antagonists – translating molecular insights in autoimmunity into effective therapy
FC09.2.3 Michael G Tovey

Immunogenicity and other problems in the use of biologicals
FC09.2.4 Niels Graudal

Similar effects of disease modifying anti rheumatic drugs, glucocorticoids and biologics on radiographic progression in rheumatoid arthritis. Meta-analysis of 70 randomised placebo or drug controlled studies including 112 comparisons
FC09.4.2 Paola Patrignani

Anti-inflammatory benefits and cardiovascular toxicity of NSAIDs and COX-2 inhibitors
FC09.4.6 Vincenzo Brancaleone

The role of formyl peptide receptor 2 (Fpr2) in leukocytes trafficking
FC09.5.1 Guy G Bruselle

Dendritic cells as targets for immunomodulation in asthma and COPD
FC09.5.7 Adam Al-Kashi

Calcitonin and glucocorticoids - a novel approach to anti-inflammatory co-therapy
FC10.1.1 Gérard Pons

Place of the innovative methodological approaches in the development of medicinal products in children
FC10.1.2 Emilio J Sanz

Increasing role of the observational approaches in the assessment of safety and efficacy of medicinal products in children
FC10.1.3 Karen I Barnes

A collaborative approach to improving the treatment of malaria: the Worldwide Antimalarial Resistance Network
FC10.2.3 Shalini Sri Ranganathan

Essential medicines list for children, what it means for the developing countries
FC10.2.4 Gregory L Kearns

Case: use of old data and modern scientific methods to provide more rational dosing and FDC formulations of TB medicines for children
FC10.3.1 Atieno Ojoo

End-user specifications for optimal paediatric formulations
FC10.3.2 Jörg Breitkreutz

Novel drug formulations for children
FC10.3.3 Anthony J Nunn

Adapting formulations for children
FC10.4.2 John N van den Anker

Developmental pharmacology of immature organs
FC10.4.3 Karel Allegaert

Neonatal analgesia: still in search of a balanced approach?
FC10.5.4 Shumpei Yokota

Use of biopharmaceuticals in pediatric field: Tocilizumab, an anti-IL-6 receptor monoclonal antibody, for children with systemic juvenile idiopathic arthritis
FC11.5.1 Bräuner-Osborne

Characterization of GPRC6A – a promiscuous 7TM receptor activated by basic L-amino acids
FC11.5.2 P Jeffrey Conn

Allosteric modulators of GPCRs as a novel approach to treatment of CNS disorders
FC12.1.2

William Catterall

Mechanisms of hyperexcitability and co-morbidities in severe myoclonic epilepsy of infancy

FC12.2.1

Sulayman D Dib-Hajj

Functional effects of sodium channel mutations in inherited chronic pain syndromes

FC12.3.2 Alfred L George

Sodium channelopathies in cardiac arrhythmia
FC12.3.4 Bernard C Rossier

Liddle’s disease and salt-dependent hypertension
FC12.4.4 Louis J Ptacek

Channels in muscle disease
FC13.1.1 Kees van Grotheest

Adverse drug reactions in hospitals
FC13.1.2 Michael A Ibara

An industry perspective of drug safety
FC13.1.3 Alasdair Breckenridge

Drug regulation and drug safety
FC13.1.4 Simon Thomas

Clinical toxicology perspective of drug safety
FC13.4.1 David B Goldstein

Safety pharmacogenomics
FC13.5.3 Jörn Lötsch

Genetic variability of pain perception and treatment
FC14.1.1 Sharon Walsh

Efficacy of current pharmacotherapies for opioid dependence: What challenges remain?
FC14.2.2 Giovanni Addolorato

Targeting GABA system: role of GABABergic drugs
FC14.3.2 Yavin Shaham

The role of the drug environment in relapse to drug seeking: lessons from rat studies
FC14.3.4 Harriet de Wit

Incubation of craving in cigarette smokers
FC14.4.2 Markus Heilig

Stress related neuropeptides: Candidate treatment targets in alcoholism
FC14.4.4 Charles Chavkin

The role of kappa-opioid transmission in dysphoric states related to stress and addiction
FC14.5.1 Harrison G Pope

Societal aspects of doping
FC14.5.3 Ruth I Wood

Anabolic-androgenic steroid addiction?  Insights from animal
FC15.3.2 Yu Huang

COX-2 products
FC15.3.4 William B Campbell

Endothelial 15-lipoxygenase eicosanoids
FC15.4.2 Csaba Szabó

Gaseous signalling molecules: the biological effects of hydrogen sulfide - comparison with nitric oxide
FC16.1.1 Valerie Schini-Kerth

Red wine polyphenols
FC16.1.2 Thomas F Lüscher

Cardioprotection by natural products: dark chocolate
FC16.2.1 Zhi-Bin Lin

Pharmacological and clinical research on Ganoderma lucidum (Lingzhi) in China
FC16.3.3 Kinzo Matsumoto

Choto-san and recognition behaviour
FC16.4.2 Arunabha Ray

Philosophy of Ayurvedic medicine and beyond
FC16.4.3 Arnold G Herman

Contributions of plant-derived products to Western medicine
FC16.5.2 Monique Simmonds

Authentication of natural products
FC16.5.4 Josephine P Briggs

Challenges in research on natural products and dietary supplements
FC17.1.2 Albert Gjedde

Cortical and subcortical dopamine receptor interactions in sensation-seeking
FC17.2.3 P Jeffrey Conn

Allosteric modulators of GPCRs for treatment of schizophrenia
FC17.3.1 Shitij Kapur

The speed and onset of antipsychotic response - implications for theory and practise
FC17.3.3 Andreas Meyer-Lindenberg

Personalized procognitive pharmacotherapy in schizophrenia
FC17.3.4 Verity J Brown

Prospectives for treatment of with cognitive enhancers or treatment of cognitive impairment
FC17.4.4 David J Nutt

Understanding Current Antidepressants’ Action as a Way to Develop Improved Therapies
FC17.5.1 Elisabeth B Binder

Using gene x environment interactions to target personalised treatment in mood disorder.
FC17.5.3 Eric Vermetten

Can brain mechanism in PTSD help direct treatment advances?
FC18.2.1 Christopher K Glass

Nuclear receptor-dependent repression mechanisms that regulate inflammation
FC18.2.3 Peter J Fuller

Mineralocorticoid receptor and vascular function
FC18.3.4 Gary E Landreth

Liver X receptors as therapeutic targets in Alzheimer's Disease
FC18.4.3 Shigeaki Kato

The role of co-regulators/co-regulator complexes in NR function
IUL Paul M Vanhoutte

The 50-Years IUPHAR Anniversary Lecture: regenerate to be old
PL01 Salvador Moncada

Vascular endothelium: physiology, pharmacology and vascular disease
PL13 Jes Olesen

New drug targets for headache
PL15 Sue P Duckles

Understanding the neuroprotective effect of estrogen; inflammation, age and mitochondria
PL16 Olavi Pelkonen

Drug metabolism - past, present and future
PL17 Morris J Brown

Therapeutic potential of vaccines in the management of hypertension
PL18 Ian E Hughes

Teaching pharmacology in 2020
PL20 Ernesto Schiffrin

Renin-angiotensin system and vascular inflammation
PL21 Thomas Lönngren

Successes and challenges in drug development - a regulatory perspective
PL23 Elisabeth Bock

New molecular targets in Alzheimer’s disease
SS01.1 Michael Davidson

Risk/benefit assessment of antipsychotic drugs in clinical practice
W01.2.2 John Ian McGrath

Localisation of adrenoceptors in live native tissue
W01.3.1 Salomon Z Langer

Possible therapeutic uses of release-modifying drugs acting on autoreceptors and neuronal transporters
W02.1.1 Gary K Beauchamp

Development of taste perception and food preference in human infants
W02.1.2 Vasiliy Zolotarev

Dietary glutamate signal evokes gastric juice excretion in dogs
W02.2.2 Sandor Szabo

The changing organ/disease targets & new molecular mechanisms in GI pharmacology
W02.2.4 Prostaglandin EP receptors and their roles in mucosal protection and ulcer healing in gastrointestinal tract
W03.1 Marcello Trevisani

TRPV1 antagonists for pain relief, cough, and incontinence
W04.1.5 Ramaronson Andriantsitohaina

Different facets of microparticles in the metabolic syndrome
W04.2.1 Ernesto Schiffrin

Anti-oxidants and cardiovascular health
W04.2.3 Valerie Schini-Kerth

Anti-oxidant potential of polyphenols
W04.2.4 Andreas Daiber

Future strategies for therapeutic use of antioxidants
W04.3.2 Urs T Ruegg

Investigations of green tea polyphenols using the mouse model of Duchenne Muscular Dystrophy
W04.3.3 Huige Li

Sirtuin1 is a molecular switch for cardiovascular oxidative stress
W04.3.4 Christopher Rembold

Success and failures in the use of anti-oxidants
W05.1 Hakki Zafer Güney

Pharmacovigilance and the role of pharmacologists - what else can be done?
W05.4 Carl-Olav Stiller

The role of clinical pharmacologists in expertorganizations recommending drugs for the greater Stockholm area
W06.2 Micheline Piquette-Miller

Inflammation-mediated alterations on drug transporters; implications on therapeutic drug response 
W06.4 Vincent Pichette

Evidence of the impact of kidney disease on drug metabolism and transport
W06.5 Patrick du Souich

Clinical and therapeutic repercussions of disease-induced down-regulation of the cytochrome P450 and of membrane transporters
W07.4 Jean Clairambault

Mathematical modelling of cell proliferation, circadian rhythm and pharmacokinetics-pharmacodynamics to optimise cancer treatments
W08.2 Ramaronson Andriantsitahoina

Different facets of microparticles in the metabolic syndrome
W08.4 Monica Montagnani

Vascular actions of insulin
W09.1 Maria José Alcaraz

Cytokines and inflammatory disease
W09.3 Santiago Redondo

Cell response of TGF-beta takes central stage in therapeutical design
W09.5 Francisco Fernandez-Aviles

Stem cell therapy for cardiac repair. Facts and hopes from a clinical point of view
W10.1 Michael Hardman

EMTRAIN - European Medicines Research Training Network
W10.2 Theodor Guentert

SafeSciMET - European modular education and training programme in Safety Sciences for Medicine
W10.3 Fritz Bühler

PharmaTrain – pharmaceutical medicines training programme
W11.3 Aletta D Kraneveld

Gut-brain and brain-gut axis revisited: possible implications in IBD and food allergy
W12.1 Asbjørn Mohr Drewes

Experimental pain and analgesics - introduction
W12.2 Lars Arendt-Nielsen

Translational human pain biomarkers in drug development
W12.4 Marieke Niesters

Ketamine: Acute and chronic pain relief and its influence on diffuse noxious inhibitory control
W12.5 Trine Andresen

Tissue differentiated effects of transdermal buprenorphine and fentanyl
W12.6 Christina Brock

Experimental pain: the role of descending inhibition and implications for drug research
W13.4 Heinz H Pertz

The role of α2C-adrenoceptors in UK14304-induced vasoconstrictor responses in rat tail arteries: potential relevance in Raynaud’s phenomenon
W14.2 Roger J Summers

Relaxin family peptides and their receptors: realising the therapeutic potential
W15.1 David B Bylund

Integrative and organ systems pharmacology
W15.3 Christian B Brink

IOSP in Africa
W16.2 Guilherme Suarez-Kurtz

Challenges of  global implementation of pharmacogenetics into clinical practice
W16.4 Andrew Somogyi

Obstacles to the implementation of pharmacogenetic testing in Australia
W16.6 Vural Özdemir

Postgenomics medicine, empiricism and ethics of bioethics: preventing both underprotection of subjects and misdirected precaution
W17.1 Michael J Mulvany

ORPHEUS: towards standards for PHd education in biomedicine and health sciences in Europe
W17.2 Nicolas Goulding

Working towards PhD standardization in the UK
W17.3 Joey W Barnett

Standards for Ph.D. Education in the United States
W17.4 Hans Orer

Setting the standards for PhD education in Turkey, keeping up with dynamisim, giving up the nonesense
W18.3 Paola Patrignani

Insights into the efficacy and risk management of COX-2 inhibitors: an example of translational medicine
W20.1 Paul White

e-learning and e-assessment in pharmacology
W20.2 Christian B Brink

Teaching pharmacology in a global arena
W20.3 Patangi K Rangachari

Active teachers/ engaged students: a status report
W20.4 Simon Maxwell

Pharmacology education for clinical students
W21.2 Jaana Rysä

Novel immunomodulatory factors in cardiac hypertrophy and heart failure
W21.3 Katja Puttonen

Neuroinflammation - Stem-cell derived neural progenitors and inflammatory response in a mouse model of cerebral stroke
W21.4 Suvi Ruohonen

Inflammation and obesity - Neuropeptide Y in pathogenesis of metabolic syndrome
W23.1 Hiroshi Watanabe

PGx from research into clinical practice (overview)
W24.1 Michel Goldman

Innovative Medicines Initiative: The EU at the forefront of novel R&D partnerships
W24.2 Christian R Noe

Challenges and opportunities in drug research
W26.1 Lars Arendt-Nielsen

Translational human pain bio-markers in early drug development
W27.4 Alexander Dodoo

Clinical testing and pharmacovigilance data for scientific evaluation of medicinal plants used in traditional medicine
W29.2 Inga Odenholdt

Prediction of individual antibiotic dose in the clinic
W30.3 Valerie Schini-Kerth

Posttranslational regulation of eNOS activity
W30.4 Huege Li

Multiple ways to target eNOS: killing N birds with one stone
W31.1 Timothy NC Wells

New medicines to improve control and contribute to the eradication of malaria
W31.3 Joao Santana da Silva

New perspectives to treat Trypanosome infection using NO donors
W31.4 Mauro M Teixeira

Anti-inflammatory strategies to treat severe infections
W32.1 Pia Caduff-Janosa

The H1N1 story: the black and the white
W32.2 Nicholas Moore

From signals to therapy
W32.3 Brian Edwards

New safety approaches towards advanced therapies
W32.4 Alex Dodoo

Between the rock and a hard place – safety monitoring of medicines for neglected diseases
W33.1 Athineos Philippu

Approaches to synaptic events in vivo under physiological and pathological conditions: state of the art
W33.4 Christina Dalla

Sex differences in animal models of depression: focus on behavioural and neurochemical manifestation
W34.1 Zoran Todorovic

Bioethical principles in pharmacology: teaching of animal bioethics at the School of Medicine, University of Belgrade
W34.3 Violeta Stanimirovic

Importance of pharmaco-toxicological evaluation of increased drug impurities and preserving drug quality and patient's safety
W34.5 Viktorija Dragojevic-Simic

Ethical committees of healthcare institutions in Serbia: Who guards patient safety?
W35.1 Petra A Thürmann

From pharmacovigilance to patient safety: prevention of adverse drug events
 


 



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16th World Congress on Basic and Clinical Pharmacology. July 17-23, 2010, Copenhagen, Denmark